Jalupro HMW and Profhilo are both injectable treatments aimed at improving the quality of the skin rather than adding volume. Because they share that goal, they are often mentioned together, and it is easy to assume they are interchangeable. They are not. This guide explains what they have in common, how they genuinely differ, and how a practitioner decides which may suit a particular person.
At Regener8 Aesthetics in Selly Oak, Birmingham, we offer both, and we choose between them based on your skin and your goals rather than on which is more fashionable.
What They Have in Common
Both treatments are injectable, both use hyaluronic acid, and both aim to improve skin quality, hydration and the appearance of firmness rather than to fill lines or reshape features. Both are typically delivered as a short course, both have minimal downtime, and both work gradually, with results developing over the weeks that follow. Importantly, neither is a dermal filler.
How They Differ
Profhilo: hyaluronic acid bio-remodelling
Profhilo is described as a bio-remodelling treatment. It is made from a high concentration of hyaluronic acid, combining high and low molecular weight forms, and is designed to spread through the skin to support hydration and stimulate the skin's own collagen and elastin. It is commonly delivered using a defined technique with a small number of set injection points per side of the face, usually as two sessions spaced about four weeks apart. You can read more in our guide to what Profhilo is.
Jalupro HMW: amino acids plus high molecular weight hyaluronic acid
Jalupro HMW is described by Jalupro as a dermal biorevitalisation treatment. Alongside high molecular weight hyaluronic acid, it provides a cluster of amino acids: glycine, L-proline, L-lysine and L-leucine. These amino acids are the building blocks the body uses in collagen-related processes. The idea is to place both hydration and these building blocks into the skin where fibroblasts are active. It is commonly delivered as a short course of small injections across the treatment area. You can read more in our guide to what Jalupro HMW is.
In short, the clearest difference is the amino acid cluster in Jalupro HMW, and the specific bio-remodelling positioning and technique associated with Profhilo.
The honest answer is that it depends on your skin, and that is exactly what a consultation is for. Book a £25 consultation and skin assessment at Regener8 Aesthetics in Selly Oak, Birmingham. The fee is fully redeemable against treatment booked within 30 days. Consultations available in English, Farsi and Russian.
Finance available, subject to approval, via our Payl8r finance partner.
Side-by-Side Comparison
| Jalupro HMW | Profhilo | |
|---|---|---|
| Category | Dermal biorevitalisation | Hyaluronic acid bio-remodelling |
| Key ingredients | High molecular weight hyaluronic acid plus amino acids (glycine, L-proline, L-lysine, L-leucine) | High and low molecular weight hyaluronic acid |
| Main aim | Support hydration and skin quality, supply collagen-related building blocks | Support hydration and stimulate the skin's own collagen and elastin |
| Adds volume? | No | No |
| Typical plan | Single treatment or a course of two, confirmed at assessment | Commonly two sessions about four weeks apart |
| Regener8 price | £185, or £340 for a course of two paid in full | £275, or £550 for a course of two |
Prices are correct at the time of publication and may change. The right plan for you is always confirmed at consultation.
Which Might Suit You?
There is no single winner. Some people are better suited to one, some to the other, and for some a different treatment entirely is more appropriate. The decision depends on your skin type, your concerns, your medical history and your goals. A practitioner will weigh these together at your assessment rather than applying a fixed rule, and will explain their reasoning so you can make an informed choice.
Neither Is a Filler
It is worth repeating, because it is the most common misunderstanding: neither Jalupro HMW nor Profhilo is a dermal filler, and neither is intended to add volume or change your facial shape. Both aim to support the quality and hydration of the skin. If your goal is volume or contour, a different conversation is needed, and your practitioner will be honest about that.
Frequently Asked Questions
- Both Jalupro HMW and Profhilo are injectable skin-quality treatments, and neither is a dermal filler.
- Profhilo is a hyaluronic acid bio-remodelling treatment; Jalupro HMW adds an amino acid cluster alongside high molecular weight hyaluronic acid.
- Both work gradually with minimal downtime and are usually delivered as a short course.
- There is no universal winner. Suitability depends on your skin and goals and is decided at assessment.
- Jalupro HMW is £185 (or £340 for two paid in full); Profhilo is £275 (or £550 for two).
Related Reading
Book a £25 consultation and skin assessment at Regener8 Aesthetics in Selly Oak, Birmingham. We will assess your skin honestly and recommend only what genuinely suits you.
Finance available, subject to approval, via our Payl8r finance partner.